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課程名稱 |
生物資訊學
Bioinformatics |
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開課學期 |
101-1 |
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授課對象 |
學程 生物產業自動化學程 |
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授課教師 |
林恩仲 |
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課號 |
AniSci7025 |
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課程識別碼 |
626 M1610 |
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班次 |
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學分 |
3 |
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全/半年 |
半年 |
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必/選修 |
選修 |
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上課時間 |
星期三2,3,4(9:10~12:10) |
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上課地點 |
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備註 |
總人數上限：40人 |
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Ceiba 課程網頁 |
http://ceiba.ntu.edu.tw/1011bioinformatics |
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課程簡介影片 |
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核心能力關聯 |
核心能力與課程規劃關聯圖 |
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課程大綱
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課程概述 |
The basic training of bioinformatics principles and tools is going to be mentioned in this course, including sequence alignment, database searching, introduction to public databases, phylogenetic analysis, gene and promoter prediction as well as function and pathway in systems biology. |
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課程目標 |
This course is designed to guide graduate students applying different bioinformatic tools to launch genomic, proteomic, and phylogenetic study. With abundant information from those public databases, students will learn how to integrate and interpret gene/gene products and related functions in gene level as well as in genomic level. |
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課程要求 |
genetics or molecular genetics/biology (or courses equivalent to) |
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預期每週課後學習時數 |
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Office Hours |
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指定閱讀 |
Zvelebil, M. and J. O. Baum. 2008. Understanding Bioinformatics. Published by: Garland Science, Taylor & Francis Group, LLC. |
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參考書目 |
Mount, D. W. 2004. Bioinformatics: Sequence and Genome Analysis. 2nd Ed.
Published by: Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY,
U.S.A. |
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評量方式
(僅供參考) |
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No. |
項目 |
百分比 |
說明 |
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1. |
HW1 |
20% |
Multiple Sequence Alignment & Motif/Pattern comparison |
2. |
HW2 |
20% |
Public database structure |
3. |
HW3 |
30% |
Phylogenetic analysis |
4. |
HW4 |
30% |
Pathway analysis |
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週次 |
日期 |
單元主題 |
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第1週 |
09/12 |
Basic of DNA, RNA and Protein (Ch.1 & 2) |
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第2週 |
09/19 |
Pairwise Sequence Alignment (Part of Ch.4 & 5: 4.6~4.10; 5.3~5.5) |
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第3週 |
09/26 |
Patterns, Profiles, and Multiple Alignment (Ch. 6; p.89~93 of 4.5) (HW1) |
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第4週 |
10/03 |
Basic of Database (Ch.3) |
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第5週 |
10/10 |
國慶日放假一天 |
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第6週 |
10/17 |
Database searching (Part of Ch.4 & 5: 4.6~4.10; 5.3~5.5) |
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第7週 |
10/24 |
Introduction to Public Databases |
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第8週 |
10/31 |
Introduction to Public Databases (HW2) |
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第9週 |
11/07 |
Introduction to Public Databases |
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第10週 |
11/14 |
Introduction to Public Databases |
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第11週 |
11/21 |
Phylogenetic Tree Reconstruction (Ch.7) |
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第12週 |
11/28 |
Generating and Evaluating Phylogenetic Tree (Ch.8) (HW3) |
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第13週 |
12/05 |
Gene and Promoter region Prediction (Ch.9) |
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第14週 |
12/12 |
Prediction of Gene Function (Ch.17) |
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第15週 |
12/19 |
Introduction to Systems Biology (Ch.17) |
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第16週 |
12/26 |
Systems Biology: Pathway analysis (HW4) |
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第17週 |
01/02 |
Practice of Pathway Analysis & Q/A |
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第18週 |
01/09 |
期末考(Final Exam) |
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